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MELK inhibitor 17
CAS No. 2095596-44-2
MELK inhibitor 17( —— )
Catalog No. M13297 CAS No. 2095596-44-2
MELK inhibitor 17 is a potent, selective MELK inhibitor with Ki/IC50 of 0.39/3 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 67 | In Stock |
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| 5MG | 110 | In Stock |
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| 10MG | 177 | In Stock |
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| 25MG | 410 | In Stock |
|
| 50MG | 605 | In Stock |
|
| 100MG | 860 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMELK inhibitor 17
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NoteResearch use only, not for human use.
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Brief DescriptionMELK inhibitor 17 is a potent, selective MELK inhibitor with Ki/IC50 of 0.39/3 nM.
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DescriptionMELK inhibitor 17 is a potent, selective MELK inhibitor with Ki/IC50 of 0.39/3 nM, >100-fold selectivity over CHK1, CAMKK2, NUAK1 and ERK2; inhibits the expression of the anti-apoptotic protein Mcl-1 and proliferation of TNBC cells exhibiting selectivity for cells expressing high levels of MELK.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetMELK
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RecptorMELK
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Research Area——
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Indication——
Chemical Information
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CAS Number2095596-44-2
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Formula Weight539.636
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Molecular FormulaC31H33N5O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 13.33 mg/mL (24.70 mM)
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SMILESO=C(C1=CC2=C(NC(/C2=C(NC3=CC=C(N(C)C(CN4CCN(C)CC4)=O)C=C3)/C5=CC=CC=C5)=O)C=C1)OC
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Chemical Namemethyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-5-carboxylate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Edupuganti R, et al. Bioorg Med Chem. 2017 May 1;25(9):2609-2616.
molnova catalog
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MELK inhibitor 17
MELK inhibitor 17 is a potent, selective MELK inhibitor with Ki/IC50 of 0.39/3 nM.
